Impact of (Integrated) Clinical Pathways on Health Care Results
a Systematic Review of the Literature
Keywords:
health care, quality of health care, clinical pathways, outcomes of health care, integrated careAbstract
Clinical pathways are recognized as a tool for ensuring the quality of health care for patients. They represent the standardization of healthcare processes to support the implementation of clinical guidelines and protocols. The aim of the study was to provide a review of the existing scientific literature and to identify the impact of (integrated) clinical pathways on healthcare outcomes. The study is based on a literature search to identify, select, and critically appraise all relevant studies from 2010 to 2020, conducted as part of the Impact of integrated clinical pathways on patient outcomes, communication and cost-effectiveness (L7-2631) application project. 35 articles were included in the content analysis. In total, 25 domains were identified where a positive impact of clinical pathways on healthcare outcomes could be demonstrated; most commonly in terms of reducing the number of complications and safety incidents, shortening the length of stay in hospital, and improving clinical treatment outcomes for patients while reducing costs. In 8 areas of these there is scientific evidence of a negative impact, and in 6 areas clinical pathways had no impact on healthcare outcomes. There is little scientific evidence of the impact of integrated clinical pathways on patient outcomes.
References
Allen, J. D., Caspi, C., Yang, M., Leyva, B., Stoddard, A. M., Tamers, S., Tucker-Seeley, R. D. and Sorensen, G. C. (2014). Pathways between acculturation and health behaviors among residents of low-income housing: the mediating role of social and contextual factors. Social Science & Medicine, št. 123, str. 26–36.
Allen, D. (2009). From boundary concept to boundary object: the politics and practices of care pathway development. Social Science & Medicine, št. 69, str. 354–361.
Allen, D., Gillen, E. and Rixson, L. (2009). A systematic review of the effectiveness of integrated care pathways: what works, for whom, in which circumstances? International Journal of EvidenceBased Healthcare, 7, št. 2, str. 61–74.
Ardito, C., Caivano, D., Colizzi, L., Dimauro, G. and Verardi, L. (2020). Design and Execution of Integrated Clinical Pathway: A Simplified Meta-Model and Associated Methodology. Information, 11, št. 7, str. 362.
Atwal, A. and Caldwell, K. (2002). Do multidisciplinary integrated care pathways improve interprofessional collaboration? Scandinavian Journal of Caring Sciences, 16, št. 4, str. 360–367.
Ažman, M. (2003). Uvajanje kliničnih poti v Splošni bolnišnici Jesenice. V: Management v operacijski zdravstveni negi: (kadrovski management): zbornik XVI, Terme Dobrna, 7. november 2003. Ljubljana: Sekcija operacijskih medicinskih sester Slovenije, str. 53–58.
Bartlett, K. W., Parente, V. M., Morales, V., Hauser, J. and McLean, H. S. (2017). Improving the Efficiency of Care for Pediatric Patients Hospitalized With Asthma. Hospital Pediatrics, 7, št. 1, str. 31–38.
Campbell, H., Hotchkiss, R., Bradshaw, N. and Porteous, M. (1998). Integrated care pathways. BMJ, 316, št. 7125, str. 133–137.
Chan, R. J., Webster, J. and Bowers, A. (2016). End-of-life care pathways for improving outcomes in caring for the dying. Cochrane Database Systematic Reviews, 12, št. 2, str. CD008006.
Dahl, T. L., Vedsted, P. and Jensen, H. (2017). The effect of standardised cancer pathways on Danish cancer patients' dissatisfaction with waiting time. Danish Medical Journal, 64, št. 1, str. A5322.
Deng,Y., Jiao, Y., Hu, R., Wang, Y., Wang, Y. and Zhao, X. (2014). Reduction of length of stay and costs through the implementation of clinical pathways for stroke management in China. Stroke, št. 45, str. e81–3.
Deneckere, S., Euwema, M., Van Herck, P., Lodewijckx, C., Panella, M., Sermeus, W. and Vanhaecht, K. (2012). Care pathways lead to better teamwork: results of a systematic review. Social Science & Medicine, 75, št. 2, str. 264–268.
De Vos, A., Dewettinck, K. and Buyens, D. (2009). The professional career on the right track: A study on the interaction between career self-management and organizational career management in explaining employee outcomes. European Journal of Work and Organizational Psychology, 18, št. 1, str. 55–80.
Doyle, C., Lennox, L. and Bell, D. A. (2013). Systematic review of evidence on the links between patient experience and clinical safety and effectiveness. BMJ Open, št. 3, str. e001570.
Du, G., Huang, L. and Zhou, M. (2020). "Variance Analysis and Handling of Clinical Pathway: An Overview of the State of Knowledge,". IEEE Access, št. 8, str. 158208–158223.
Elliott, M. J., Gil, S., Hemmelgarn, B. R., Manns, B. J., Tonelli, M., Jun, M. and Donald, M. (2017). A scoping review of adult chronic kidney disease clinical pathways for primary care. Nephrol Dial Transplant, 32, št. 5, str. 838–846.
Emeđi, D. and Skela-Savič, B. (2015). Povezave med razjedo zaradi pritiska in ohranjanjem integritete kože pacienta v intenzivni zdravstveni obravnavi: pregled literature. Obzornik zdravstvene nege, 49, št. 4, str. 309.
EPA (2018). EPA Care Pathways. 2018a. Pridobljeno dne 23. 1. 2021 s http://e-p-a.org/carepathways.
Furuhata, H., Araki, K., Ogawa, T. and Ikeda, M. (2017). Effect on Completion of Clinical Pathway for Improving Clinical Indicator: Cases of Hospital Stay, Mortality Rate, and ComprehensiveVolume Ratio. Journal of Medical Systems, 41, št. 12, str. 206.
Goljar, N. (2016). Oblikovanje nove klinične poti na Univerzitetnem rehabilitacijskem inštitutu Republike Slovenije – Soča Designing a new clinical pathway at the University Rehabilitation Institute in Ljubljana, Rehabilitacija (Ljubljana), 15, št. 1, str. 8–11.
Greaves, F., Pappas, Y., Bardsley, M., Harris, M., Curry, N., Holder, H., Blunt, I., Soljak, M., Gunn, L., Majeed, A. and Car, J. (2013). Evaluation of complex integrated care programmes: the approach in North West London. International Journal of Integrated Care, št. 13, str. e006.
Hai, J. J., Wong, C. K., Un, K. C., Wong, K. L., Zhang, Z. Y., Chan, P. H. idr. (2019). GuidelineBased Critical Care Pathway Improves Long-Term Clinical Outcomes in Patients with Acute Coronary Syndrome. Scientific Reports, št. 9, str. 16814.
Hanefeld, J., Powell-Jackson, T. and Balabanova, D. (2017). Understanding and measuring quality of care: dealing with complexity. Bulletin of the World Health Organization, 95, št. 5, str. 368–374.
Hogan, K., Barry, M. in Burke, M. (2011). Healthcare professionals' experiences of the implementation of integrated care pathways. International Journal of Health Care Quality Assurance, 24, št. 5, str. 334–347.
Hoverman, J. R., Cartwright, T. H., Patt, D. A., Espirito, J. L., Clayton, M. P., Garey, J. S., Kopp, T. J., Kolodziej, M., Neubauer, M. A., Fitch, K., Pyenson, B. and Beveridge, R. A. (2011). Pathways, outcomes, and costs in colon cancer: retrospective evaluations in two distinct databases. Journal of oncology practice, 7, št. 3, str. 52s–9s.
Hussain, Z. I., Lim, M. and Stojkovic, S. (2017). Role of clinical pathway in improving the quality of care for patients with faecal incontinence: A randomised trial. World Journal of Gastrointestinal Pharmacology and Therapeutics, 8, št. 1, str. 81–89.
Ismail, S., Osman, M., Abulezz, R., Alhamdan, H. and Quadri, K. H. M. (2018). Pharmacists as Interprofessional Collaborators and Leaders through Clinical Pathways. Pharmacy (Basel), 6, št. 1, str. 24.
Jeong, S. H. , Yoo, M. W., Yoon, H. M., Lee, H. J., Ahn, H. S., Cho, J. J. idr. (2011). Is the critical pathway effective for the treatment of gastric cancer? Journal of the Korean Surgical Society, 81, št. 2, str. 96–103.
Kebapcı, A. and Kanan, N. (2018). Effects of nurse-led clinical pathway in coronary artery bypass graft surgery: A quasi-experimental study. Journal of Clinical Nursing, 27, št. 5–6, str. 980–988.
Kolk, M., Boogaard, M. H. W. A., Becking-Verhaar, F., Custers, H., Hoeven, H., Pickkers, P. and Laarhoven, K. (2017). Implementation and Evaluation of a Clinical Pathway for Pancreaticoduodenectomy Procedures: a Prospective Cohort Study. Journal of Gastrointestinal
Surgery, 21, št. 9, str. 1428–1441.
Lawal, A., Groot, G., Goodridge, D., Shannon D. and Scott, D. S. (2019). Development of a program theory for clinical pathways in hospitals: protocol for a realist review. Systematic Reviews, 8, št. 1.
Leigheb, F., Vanhaecht, K., Sermeus, W., Lodewijckx, C., Deneckere, S., Boonen, S., Boto, P. A., Mendes, R. V. and Panella, M. (2012). The effect of care pathways for hip fractures: a systematic review. Calcified Tissue International, 91, št. 1, str. 1–14.
Li, W., Liu, K., Yang, H. and Yu, C. (2014). Integrated clinical pathway management for medical quality improvement - Based on a semiotically inspired systems architecture. European Journal of Information Systems, 23, št. 4, str. 400–417.
Lifland, B., Wright, D. R., Mangione-Smith, R. and Desai, A. D. (2018). The Impact of an Adolescent Depressive Disorders Clinical Pathway on Healthcare Utilization. Administration and Policy in Mental Health and Mental Health Services Research, 45, št. 6, št. 979–987.
Lion, K. C., Wright, D. R., Spencer, S., Zhou, C., Del Beccaro, M. and Mangione-Smith, R. (2016). Standardizirane klinične poti za hospitalizirane otroke in izidi. Pediatrija, 137, št. 4, str. e20151202.
Lodewijckx, C., Sermeus, W., Panella, M., Deneckere, S., Leigheb, F., Decramer, M. and Vanhaecht, K. (2011). Impact of a care pathway for COPD on adherence to guidelines and hospital readmission: a cluster randomized trial. Int J Nurs Stud., 48, št. 11, str. 1445–1456.
Martin, G. P., Kocman, K., Stephens T., Peden, C. J. and Rupert, M. (2017). Pearse Pathways to professionalism? Quality improvement, care pathways, and the interplay of standardisation and clinical autonomy. Sociology of Health & Illness, 39, št. 8, str. 1314–1329.
Marušič, D. in Simčič, B. (2009). Priročnik za oblikovanje kliničnih poti. Ljubljana: Ministrstvo za zdravje.
Middleton, S. and Roberts, A. (2003). Integrated care pathways: a practical approach to implementation. Edinburg : Butterworth Heinemann.
Neame, M. T., Chacko, J., Surace, A. E., Sinha, I. P. and Hawcutt, D. B. (2019). A systematic review of the effects of implementing clinical pathways supported by health information technologies. Journal of the American Medical Informatics Association, 26 št. 4, str. 356–363.
OECD (2019). Improving healthcare quality in Europe Characteristics, effectiveness and implementation of different strategies. Pridobljeno dne 23. 1. 2021 s svetovnega spleta: htps://apps.who.int/iris/bitstream/handle/10665/327356/9789289051750-eng.pdf?sequence=1&isAllowed=y.
Plishka, C. T., Rotter, T., Penz, E. D., Hansia, M. R., Fraser, S. A., Marciniuk, D. D. and Saskatchewan C. O. P. D CPW Research Group. (2019). Effects of Clinical Pathways for COPD on Patient, Professional, and Systems Outcomes: A Systematic Review. Chest Journal, 156, št. 5, str. 864–877.
Polit, D. F. and Beck, C. T. (2014). Essentials of Nursing Research. 8th edition. Philadelphia: Wolters Kluver Health, Lippicott, William & Wilkins.
Rems, M., Tušar, S. and Mezek, M. (2003). Prve izkušnje z uvajanjem klinične poti za laparoskopsko holecistektomijo. Endoskopska revija: glasilo Sekcije za endoskopsko kirurgijo in Sekcije za gastroenterološko endoskopijo Slovenije, 8, št. 19, str. 36.
Rotter, T., Kinsman, L., James, E., Machotta, A. and Steyerberg, E. W. (2012). The quality of the evidence base for clinical pathway effectiveness: room for improvement in the design of evaluation trials. BMC Medical Research Methodology, 18, št. 12, str. 80.
Rotter, T., Kinsman, L., James, E., Machotta, A., Gothe, H., Willis, J., Snow, P. and Kugler, J. (2010). Clinical pathways: effects on professional practice, patient outcomes, length of stay and hospital costs. Cochrane Database Systematic Reviews, 17, št. 3, str. CD006632.
Seehusen, D. A. (2010). Clinical pathways: effects on practice, outcomes, and costs. American Academy of Family Physicians, 82, št. 11, str. 1338–1339.
Simpson, J. C., Moonesinghe, S. R., Grocott, M. P. W., Kuper, M., McMeeking, A., Oliver, C. M., idr. (2015) Enhanced recovery fromsurgery in the UK: An audit of the enhanced recovery partnership programme 2009–2012, British Journal of Anaesthesia, 115, št. 4, str. 560–568.
Simpson idr., 2015 impson, J.C., Moonesinghe, S.R., Grocott, M.P.W., Kuper, M., et al. (2015) Enhanced recovery from surgery in the UK: An audit of the enhanced recovery partnership programme 2009–2012, British Journal of Anaesthesia, 115, št. 4, str. 560–568.
Sylvester, A. M.and George, M. (2014). Effect of a clinical pathway on length of stay and cost of pediatric inpatient asthma admissions: an integrative review. Clinical Nursing Research, 23, št. 4, str. 384–401.
Stokes, T., Tumilty, E., Doolan - Noble, F. and Gauld, R. (2018). HealthPathways implementation in a New Zealand health region: a qualitative study using the Consolidated Framework for Implementation Research. BMJ Open, 8, št. 12, str. e025094.
Sullivan, D. O., Manix, M. and Timmons, S. (2017). Integrated Care Pathways and Care Bundles for Dementia in Acute Care: Concept Versus Evidence. American Journal of Alzheimer’s Disease & Other Dementias®, 32, št. 4, str. 189–193.
Tarin, T., Feifer, A., Kimm, S., Chen, L., Sjoberg, D., Coleman, J. and Russo, P. (2014). Impact of a common clinical pathway on length of hospital stay in patients undergoing open and minimally invasive kidney surgery. Journal of Urology, 191, št. 5, str. 1225–1230.
Tastan, S., Hatipoglu, S., Iyigun, E. and Kilic, S. (2012). Implementation of a clinical pathway in breast cancer patients undergoing breast surgery. European Journal of Oncology Nursing, 16, št. 4, str. 368–374.
Thursky, K., Lingaratnam, S., Jayarajan, J., Haeusler, G. M., Teh, B., Tew, M. idr. (2018). Implementation of a whole of hospital sepsis clinical pathway in a cancer hospital: impact on sepsis management, outcomes and costs. BMJ Open Quality, 7, št. 3, str. e000355.
Yetzer, J. G., Pirgousis, P., Li, Z. and Fernandes, R. (2017). Clinical Pathway Implementation Improves Efficiency of Care in a Maxillofacial Head and Neck Surgery Unit. Journal of Oral and Maxillofacial Surgery, 75, št. 1, str. 190–196.
Valentijn, P. P., Pereira, F., Sterner, C. W., Vrijhoef, H. J. M., Ruwaard, D., Hegbrant, J. and Strippoli, G. F. M. (2019). Validation of the Rainbow Model of Integrated Care Measurement Tools (RMIC-MTs) in renal care for patient and care providers. PLoS One, 14, št. 9, str. e0222593.
Van Hoeve, J. C., Vernooij, R. W. M., Fiander, M., Nieboer, P., Siesling, S. and Rotter, T. (2020). Effects of oncological care pathways in primary and secondary care on patient, professional and health systems outcomes: a systematic review and meta-analysis. Systematic Reviews, 9, št. 246.
Weizi, L., Kecheng, L., Hongqiao, Y. and Changrui, Y. (2014). Integrated clinical pathway management for medical quality improvement – based on a semiotically inspired systems architecture. European Journal of Information Systems, 23, št. 4, str. 400–417.
Weldring, T. and Smith, S. M. (2013). Patient-Reported Outcomes (PROs) and PatientReported Outcome Measures (PROMs). Health Services Insights, št. 6, str. 61–68.
Williams, J. E., Peacock, J., Gubbay, A. N., Kuo, P. Y., Ellard, R., Gupta, R. idr. (2015). Routine screening for pain combined with a pain treatment protocol in head and neck cancer: a randomised controlled trial. British Journal of Anaesthesia, 115, št. 4, str. 621–628.




