Relationship between Physical Activity in Middle Age and Dementia Risk
Keywords:
physical activity, midlife, cognitive decline, dementiaAbstract
Dementia is a set of symptoms or disabilities, a disorder of several higher cortical, cognitive and intellectual functions. The development of dementia is associated with lifestyle in middle age. Physical activity is considered an important protective factor for health. The purpose of this study was to determine the correlation of physical activity in middle age with dementia risk and the incidence of dementia and cognitive health in old age. Through a systematic review over a five-year period, we found
that the authors unanimously agree that even mild and moderate physical activity is sufficient to reduce the risk of cognitive decline and all types of dementia. The results are divided on the intensity of physical activity, association with dementia risk, incidence of different types of dementia and cognitive health. Current scientific evidence does not support the development of uniform guidelines on physical activity for the prevention of dementia and cognitive decline. There is an opportunity to provide physical activity recommendations in a new study focusing on the middle-aged population in the context of identifying dementia and cognitive health.
References
DeFina, L. F., Haskell, W. L., Willis, B. L., Barlow, C. E., Finley, C. E., Levine, B. D. and Cooper, K. H. (2015). Physical Activity Versus Cardiorespiratory Fitness: Two (Partly) Distinct Components of Cardiovascular Health? Progress in Cardiovascular Diseases, 57, št. 4, str. 324–329.
Flainer, T., Dauth, H., Gersie, M., Zijlstra, W. and Haussemann, P. (2017). Structured physical exercise improves neuropsychiatric symptoms in acute dementia care: a hospital-based RCT. Alzheimerʹs Research and Therapy, 9, št. 68, str. 1–9.
Greenhalgh, T. (2014). How to read a Paper: The basics of evidence based medicine. 5th ed. London: BMJ.
Gross, A. L., Lu, H., Meoni, L., Gallo, J. J., Schrack, J. A. and Sharrett, A. R. (2017). Physical Activity in Midlife is not Associated with Cognitive Health in Later Life Among Cognitively Normal Older Adults. Journal of Alzheimer’s Disease, 59, št. 4, str. 1349–1358.
Guure, C. B., Ibrahim, N. A., Adam, M. B. and Said, S. M. (2017). Impact of Physical Activity on Cognitive Decline, Dementia, and Its Subtypes: Meta-Analysis of Prospective Studies. BioMed Research International, str. 1–13.
Hansson, O., Svensson, M., Gustavsson, A.-M., Andersson, E., Yang, Y., Nägga, K., Hållmarker, U., James, S. and Deierborg, T. (2019). Midlife physical activity is associated with lower incidence of vascular dementia but not Alzheimer’s disease. Alzheimer’s Research and Therapy, 11, št. 87, str. 1–15.
Hörder, H., Johansson, L., Guo, X., Grimby, G., Kern, S., Östling, S. and Skoog, I. (2018). Midlife cardiovascular fitness and dementia. Neurology, 90, št. 15, str. e1298–e1305.
Iso - Markku, P., Waller, K., Kujala, U. M. and Kaprio, J. (2015). Physical activity and dementia: Long-term follow-up study of adult twins. Annals of Medicine, 4, št. 2, str. 81–87.
Iso - Markku, P., Waller, K., Vuoksimaa, E., Heikkilä, K., Rinne, J., Kaprio, J. and Kujala, U. M. (2016). Midlife Physical Activity and Cognition Later in Life: A Prospective Twin Study. Journal of Alzheimer’s Disease, 54, št. 4, str. 1303–131.
Krell - Roesch, J., Pink, A., Roberts, R. O., Stokin, G. B., Mielke, M. M., Spangehl, K. A., Bartley, M. M., Knopman, D. S., Christianson, T. J. H., Petersen, R. C. and Geda, Y. E. (2016). Timing of Physical Activity, Apolipoprotein Eε4 Genotype, and Risk of Incident Mild Cognitive Impairment. Journal of the American Geriatrics Society, 6, št. 12, str. 2479–2486.
Lam, F. M. H., Huang, M. Z., Liao, L. R., Chung, R. C. K., Kwok, T. C. Y. and Pang, M. Y. C. (2018). Physical exercise improves strength, balance, mobility, and endurance in people with cognitive impairment and dementia: a systematic review. Journal of Physiotherapy, 64, str. 4–15.
Najar, J., Östling, S., Gudmundsson, P., Sundh, V., Johansson, L., Kern, S., Guo, X., Hallstrom, T. and Skoog, I. (2019). Cognitive and physical activity and dementia: A 44-year longitudinal population study of women. Neurology, 92, št. 12, str. e1322–e1330.
Ogino, E., Manly, J. J., Schupf, N., Mayeux, R. and Gu, Y. (2019). Current and Past leisure time physical activity in relation to risk of Alzheimer’s disease in older adults. Alzheimer’s and Dementia, 15, št. 12, str. 1603–1611.
Palta, P., Sharrett, A. R., Deal, J. A., Evenson, K. R., Gabriel, K. P., Folsom, A. R., Gross, A.L., Windham, B. G., Knopman, D., Mosley, T. H. and Heiss, G. (2018). Leisure-time physical activity sustained since midlife and preservation of cognitive function: The Atherosclerosis Risk in Communities study cohort. Alzheimer’s and Dementia, 15, št. 2, str. 273–281.
Pirtošek, Z. (2016). Pomembna je zgodnja prepoznava bolezni. Spominčica: glasilo Slovensko združenje za pomoč pri demenci, 14, št. 1, str. 14–15.
Raz, L., Knoefel, J. and Bhaskar, K. (2016). The neuropathology and cerebrovascular mechanisms of dementia. Journal of Berebral Blood Flow and Metabolism, 36, št. 1, str. 172–186.
Rugelj, D. (2012). V ravnotežje usmerjena vadba: povezanost gibalnih in spoznavnih aktivnosti. Rehabilitacija, 11, št. 1, str. 51–58.
Sabia, S., Dugravot, A., Dartigues, J.-F., Abell, J., Elbaz, A., Kivimäki, M. and Singh - Manoux, A. (2017). Physical activity, cognitive decline, and risk of dementia: 28 year follow-up of Whitehall II cohort study. BMJ, 357, št. j2709, str. 1–12.
Stephen, R., Hongisto, K., Solomon, A. and Lönnroos, E. (2017). Physical Activity and Alzheimer’s Disease: A Systematic Review. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 72, št. 6, str. 733–739.
Strojnik, V. (2016). Gibanje in demenca. Spominčica: glasilo Slovensko združenje za pomoč pri demenci, 14, št. 1, str. 14–15.
Tolppanen, A.-M., Solomon, A., Kulmala, J., Kåreholt, I., Ngandu, T., Rusanen, M., Laatikainen, T., Soininen, H. and Kivipelto, M. (2015). Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia. Alzheimer’s and Dementia, 11, št. 4, str. 434–443.
Tsenkova, V. K. (2017). Leisure-time, occupational, household physical activity and insulin resistance (HOMAIR) in the Midlife in the United States (MIDUS) national study of adults. Preventive Medicine Reports, 5, str. 224–227.
Welch, V., Petticrew, M., Tugwell, P., Moher, D., O'Neill, J., Waters, E. and White, H. (2012). PRISMA-Equity 2012 Extension: Reporting Guidelines for Systematic Reviews with a Focus on Health Equity. PLoS Med, 9, št. 10, str. e1001333.
World health organization (2020). WHO guidelines on Physical Activity and Sedentary behaviour. Ženeva, str. 15–46. Pridobljeno s svetovnega spleta: https://www.who.int/publications/i/item/9789240015128.
Xu, W., Wang, H. F., Wan, Y., Tan, C.-C., Yu, J.-T. and Tan, L. (2017). Leisure time physical activity and dementia risk: a dose-response meta-analysis of prospective studies. BMJ Open, 7, št. 10, e014706, str. 1–10.
Zotcheva, E., Bergh, S., Selbæk, G., Krokstad, S., Håberg, A. K., Strand, B. H. and Ernstsen, L. (2018). Midlife Physical Activity, Psychological Distress, and Dementia Risk: The HUNT Study. Journal of Alzheimer’s Disease, 66, št. 2, str. 825–833.




